This two-volume set (CCIS 1762-1763) constitutes the refereed proceedings of the 4th International Conference on Machine Learning, Image Processing, Network Security and Data Sciences, MIND 2022, held in Bhopal, India, in December 2022. The 64 papers presented in this two-volume set were thoroughly reviewed and selected from 399 submissions. The papers are organized according to the following topical sections: machine learning and computational intelligence; data sciences; image processing and computer vision; network and cyber security.