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Perfusion Cell Culture Processes for Biopharmaceuticals

Process Development, Design, and Scale-up

; Jean-Marc Bielser ; Massimo Morbidelli

Master the design and operation of perfusion cell cultures with this authoritative reference. Discover the current state-of-the-art in the design and operation of continuous bioreactors, with emphasis on mammalian cell cultures for producing therapeutic proteins. Les mer
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Vår pris: 1519,-

(Innbundet) Fri frakt!
Leveringstid: Sendes innen 21 dager
På grunn av Brexit-tilpasninger og tiltak for å begrense covid-19 kan det dessverre oppstå forsinket levering.

Om boka

Master the design and operation of perfusion cell cultures with this authoritative reference. Discover the current state-of-the-art in the design and operation of continuous bioreactors, with emphasis on mammalian cell cultures for producing therapeutic proteins. Topics include the current market for recombinant therapeutic proteins, current industry challenges and the potential contribution of continuous manufacturing. Provides coverage of every step of process development and reactor operation, including small scale screening to lab-scale and scale-up to manufacturing scale. Illustrated through real-life case studies, this is a perfect resource for groups active in the cell culture field, as well as graduate students in areas such as chemical engineering, biotechnology, chemistry and biology, and to those in the pharmaceutical industry, particularly biopharma, biotechnology and food or agro industry.

Fakta

Innholdsfortegnelse

1. Perfusion mammalian cell culture for recombinant protein manufacturing; 2. Perfusion bioreactors; 3. Scale-down models and sensors for process development; 4. Design and optimization of mammalian cell perfusion cultures; 5. Clinical and commercial-scale reactors; 6. Mechanistic and statistical modeling of bioprocesses.

Om forfatteren

Master the design and operation of perfusion cell cultures with this authoritative reference.Moritz Wolf is a management consultant at McKinsey & Company and a former post-doctoral fellow at ETH Zurich in the department of Chemistry and Applied Biosciences. He has obtained the degree of Doctor of Science from ETH Zurich. Jean-Marc Bielser is an associate manager in the Biopharma Technology and Innovation group at Merck Serono SA (Switzerland). He obtained his master in Chemical Engineering and Biotechnology from EPFL, and the degree of Doctor of Science from ETH Zurich. Massimo Morbidelli is Professor Emeritus in the Department of Chemistry and Applied Biosciences at ETH Zurich and Professor at the Department of Chemistry, Materials and Chemical Engineering at the Politecnico di Milano. Member of the Italian Academy of Sciences (Accademia dei Lincei), he received the Excellence in Process Development Research Award in 2017 from the American Institute of Chemical Engineers, the 2018 Separations Science and Technology Award from the American Chemical Society and the 2019 Award in Integrated Continuous Biomanufacturing. He is the co-author of Continuous Biopharmaceutical Processes (Cambridge, 2018), and Parametric Sensitivity in Chemical Systems (Cambridge, 2005).