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Xiaolu Guo was born in south China. She studied at the Beijing Film Academy and published six books in China before moving to London in 2002. Her books include Village of Stone which was shortlisted for the Independent Foreign Fiction Prize, A Concise Chinese-English Dictionary for Lovers which was shortlisted for the Orange Prize, 20 Fragments of a Ravenous Youth which was longlisted for the Man Asian Literary Prize, and I Am China which was longlisted for the Women's Prize for Fiction. Her recent memoir, Once Upon a Time in the East, won the National Book Critics Circle Award, was shortlisted for the Costa Biography Award, the Jhalak Prize and the Rathbones Folio Award 2018, and was a Sunday Times Book of the Year.

In 2013 Xiaolu was named as one of Granta's Best of Young British Novelists. She has directed several award-winning films including She, A Chinese, and documentaries about China and Britain. She was a judge for the Booker Prize in 2019, and is currently a visiting professor at Columbia University in New York.