The publication covers the 49 regional members of ADB. It discusses trends in development progress and the challenges to achieving inclusive and sustainable economic growth across Asia and the Pacific. This 53rd edition finds that the COVID-19 pandemic has set back the fight against poverty in the region by at least 2 years. Drawing on data simulations, it concludes that people with less social mobility may experience longer-lasting difficulties in escaping poverty. Key Indicators for Asia and the Pacific 2022 includes a special chapter on how data resilience can be achieved in the wake of pandemic disruptions to the operations of national statistical systems. The publication is complemented by a special supplement, Mapping the Public Voice for Development: Natural Language Processing of Social Media Text Data, which explores how social media text data can be harnessed to help policymakers understand the opinions, ideas, and expectations of the public.